Neurotrophin-mediated rapid signaling in the central nervous system: mechanisms and functions.
نویسندگان
چکیده
Neurotrophins regulate growth, survival, and differentiation of central neurons. In addition to the "classical" effects that are relatively slow neurotrophins also elicit rapid signaling that modulates a variety of cellular functions such as membrane excitability, synaptic transmission, and activity-dependent synaptic plasticity. These rapid actions are mediated mainly through the interaction of Trk receptors with ion channels and ionotropic receptors in the plasma membrane.
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عنوان ژورنال:
- Physiology
دوره 20 شماره
صفحات -
تاریخ انتشار 2005